Q: What is the function of the target CD19?
A: CD19 is a protein that plays a crucial role in establishing intrinsic B cell signaling thresholds via modulating both B cell receptor (BCR)-dependent and independent signaling. It is predominantly expressed on B cells, making it a potential target for therapies focused on B cell malignancies such as certain types of lymphoma and leukemia. CD19 is also important in the development of the immune system. It is required for normal differentiation of B-1 cells and normal B cell differentiation and proliferation in response to antigen challenges and maintenance of normal levels of serum immunoglobulins. Therapies may be designed to bind to CD19, leading to the destruction or inhibition of the B cells that express it.

Q: What is the storage recommendation for this product?
A: The product should be stored at 4°C in the dark.

Q: What type of product is the PE-Cy5-conjugated anti-mouse CD19 monoclonal antibody?
A: Anti-Mouse CD19 IgA Monoclonal Antibody (MB19-1)-PE Cy5 is a monoclonal antibody generated from the mouse, which is designed to bind to the CD19 protein on B cells. It is used in scientific research, generally to identify, count, or eliminate B cells, or to explore B cell behavior and involvement in diseases. The PE Cy5 designation refers to the type of fluorescent tag on the antibody, which helps in its detection.

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