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This product is an unconjugated anti-mouse CD19 monoclonal antibody gernerated from the mouse. This antibody can be used for applications: Flow Cytometry/FACS, Immunofluorescence.
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specifications |
|
|---|---|
| Antibody Isotype | IgA |
| Clone | MB19-1 |
| Applications | FC; IF |
| Target | CD19 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Mouse |
| Immunogen | CD19+ mouse pre-B cell line |
| Format | Liquid |
| Buffer | Borate Buffered Saline, pH 8.2 |
| Storage | Store at 4°C. Avoid repeated freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | CD19 |
| Alternative Names | CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; B-Lymphocyte Antigen CD19; CD19 Antigen; CVID3 |
| Related Disease | Immunodeficiency Common Variable 3; Common Variable Immunodeficiency |
| Gene ID | 930 |
| UniProt ID | P15391 |
| Target Overview | Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.
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Datasheet
