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This product is a APC-conjugated anti-mouse CD19 monoclonal antibody gernerated from the mouse. This antibody can be used for Flow Cytometry/FACS.
Please feel free to contact us for a quote and further discussion with our scientists. Datasheets
specifications |
|
|---|---|
| Antibody Isotype | IgA |
| Clone | MB19-1 |
| Applications | FC |
| Target | CD19 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Mouse |
| Immunogen | CD19+ mouse pre-B cell line |
| Format | Liquid |
| Buffer | PBS, pH 7.2 |
| Storage | Store at 4°C in the dark. |
Target Information |
|
|---|---|
| Target Name | CD19 |
| Alternative Names | CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; B-Lymphocyte Antigen CD19; CD19 Antigen; CVID3 |
| Related Disease | Immunodeficiency Common Variable 3; Common Variable Immunodeficiency |
| Gene ID | 930 |
| UniProt ID | P15391 |
| Target Overview | Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge. |
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!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.
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Datasheet
