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This product is a FITC-conjugated anti-mouse CD19 monoclonal antibody gernerated from the mouse. This antibody can be used for Flow Cytometry/FACS.
Please feel free to contact us for a quote and further discussion with our scientists. Datasheets
specifications |
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Antibody Isotype | IgA |
Clone | MB19-1 |
Applications | FC |
Target | CD19 |
Host | Mouse |
Clonality | Monoclonal |
Antibody Type | Primary antibody |
Species Reactivity | Mouse |
Immunogen | CD19+ mouse pre-B cell line |
Format | Liquid |
Buffer | PBS, pH 7.2 |
Storage | Store at 4°C in the dark. |
Target Information |
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Target Name | CD19 |
Alternative Names | CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; B-Lymphocyte Antigen CD19; CD19 Antigen; CVID3 |
Related Disease | Immunodeficiency Common Variable 3; Common Variable Immunodeficiency |
Gene ID | 930 |
UniProt ID | P15391 |
Target Overview | Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2+ stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
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