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This product is a conjugated anti-Mouse CD207 Monoclonal antibody (205C1) generated from the Mouse. This antibody can be used for FC, IF.
Please feel free to contact us for a quote and further discussion with our scientists. Datasheets
specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | 205C1 |
| Applications | FC; IF |
| Target | CD207 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Mouse |
| Immunogen | CD207 |
| Format | Liquid |
| Buffer | PBS and 50% Glycerol |
| Storage | Store at 4° C in dark. Do not freeze. |
Target Information |
|
|---|---|
| Target Name | CD207 |
| Alternative Names | Langerin; CD207 Molecule; CLEC4K; C-Type Lectin Domain Family 4 Member K; Langerhans Cell Specific C-Type Lectin |
| Related Disease | Birbeck Granule Deficiency; Langerhans Cell Histiocytosis |
| Gene ID | 50489 |
| UniProt ID | Q9UJ71 |
| Target Overview | Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. |
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Datasheet
