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Mouse Anti-Mouse CD207 IgM Monoclonal Antibody (205C1) (CAT#: NGM-085)

This product is an unconjugated anti-Mouse CD207 Monoclonal antibody (205C1) generated from the Mouse. This antibody can be used for ChIP, FC, IF.

Please feel free to contact us for a quote and further discussion with our scientists. Datasheets


Antibody Isotype IgM
Clone 205C1
Applications ChIP; FC; IF
Target CD207
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Mouse
Immunogen CD207
Format Liquid
Buffer Tris-NaCl, pH 8.0
Storage Store at -20° C to -80° C. Avoid freeze-thaw cycles.

Target Information

Target Name CD207
Alternative Names Langerin; CD207 Molecule; CLEC4K; C-Type Lectin Domain Family 4 Member K; Langerhans Cell Specific C-Type Lectin
Related Disease Birbeck Granule Deficiency; Langerhans Cell Histiocytosis
Gene ID 50489
UniProt ID Q9UJ71
Target Overview Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.






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