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This product is a conjugated anti-Mouse CD49b Monoclonal antibody (DX5) generated from the Rat. This antibody can be used for FC.
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specifications |
|
|---|---|
| Antibody Isotype | IgM, κ |
| Clone | DX5 |
| Applications | FC |
| Target | CD49b |
| Host | Rat |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Mouse |
| Immunogen | RIL-2 propagated NK1.1+ cells from C57BL/6 mice |
| Format | Liquid |
| Buffer | PBS with 0.1% gelatin, pH 7.2 |
| Storage | Store at 4° C in dark. Do not freeze. |
Target Information |
|
|---|---|
| Target Name | CD49b |
| Alternative Names | Integrin Subunit Alpha 2; Integrin, Alpha 2 (CD49B, Alpha 2 Subunit Of VLA-2 Receptor); Alpha 2 Subunit Of VLA-2 Receptor; CD49 Antigen-Like Family Member B; Platelet Membrane Glycoprotein Ia; Collagen Receptor; Integrin Alpha-2; CD49B; GPIa; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; Human Platelet Alloantigen System 5; Platelet Glycoprotein GPIa; Platelet Antigen Br; VLA-2 Subunit Alpha; CD49b Antigen; HPA-5; VLA-2; VLAA2; ITGA2 |
| Related Disease | Bleeding Disorder Platelet-Type 9; Bleeding Disorder Platelet-Type 11 |
| Gene ID | 16398 |
| UniProt ID | Q62469 |
| Target Overview | Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A. Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8. |
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Datasheet
