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This product is an unconjugated anti-Human TNFSF13B Monoclonal antibody (Buffy-2) generated from the Rat. This antibody can be used for WB, FC, IHC.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | Buffy-2 |
| Applications | WB; FC; IHC |
| Target | TNFSF13B |
| Host | Rat |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant human soluble BAFF, aa., 3-285 |
| Format | Liquid |
| Buffer | PBS |
| Storage | Store at -20° C to -80° C. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | TNFSF13B |
| Alternative Names | TNF Superfamily Member 13b; B-Cell-Activating Factor; TALL1; BAFF; BLYS; Tumor Necrosis Factor Ligand Superfamily Member 13B; TNF And ApoL-Related Leukocyte Expressed Ligand 1; Dendritic Cell-Derived TNF Like Molecule; TNF Homolog That Activates Apoptosis; B-Lymphocyte Stimulator; TNFSF20; CD257; THANK; ZTNF4; Delta BAFF |
| Related Disease | Sialadenitis; Igg4-Related Disease |
| Gene ID | 10673 |
| UniProt ID | Q9Y275 |
| Target Overview | TNF Superfamily Member 13b is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. |
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Datasheet
