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This product is an unconjugated anti-Toll-like receptor 3 Monoclonal antibody (619F7.06) generated from the Mouse. This antibody can be used for WB, FC, IF, IHC.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | 619F7.06 |
| Applications | WB; FC; IF; IHC |
| Target | Toll-like receptor 3 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human, Mouse, Rat, Canine |
| Immunogen | Toll Like Receptor 3 |
| Format | Liquid |
| Buffer | Tris-NaCl, pH 8.0 |
| Storage | Store at -20° C to -80° C. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | Toll-like receptor 3 |
| Alternative Names | CD283; IIAE2; TLR3 |
| Related Disease | Encephalopathy Acute Infection-Induced 2; Human Immunodeficiency Virus Type 1 |
| Gene ID | 7098 |
| UniProt ID | O15455 |
| Target Overview | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.
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Datasheet
