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This product is an unconjugated anti-Thrombospondin 1 Monoclonal antibody (A4.1) generated from the Mouse. This antibody can be used for WB, FC, IF.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | A4.1 |
| Applications | WB; FC; IF |
| Target | Thrombospondin 1 |
| Epitope | This antibody recognizes an epitope in the N-terminal half of the central stalk-like region of TSP 1 which is recovered as a 50 kDa fragment after chymotryptic digestion of TSP. |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human, Mouse, Rat, Bovine, Chicken |
| Immunogen | Calcium-replete, native purified human Thrombospondin 1 from the supernatant of thrombin-activated platelets |
| Format | Liquid |
| Buffer | PBS with 0.2% BSA, pH 7.4 |
| Storage | Store at 4° C. |
Target Information |
|
|---|---|
| Target Name | Thrombospondin 1 |
| Alternative Names | TSP1; TSP; Thrombospondin-1p180; Thrombospondin-1; Glycoprotein G; THBS-1; THBS; Thrombospondin-P50; THBS1 |
| Related Disease | Thrombotic Thrombocytopenic Purpura; Peters-Plus Syndrome |
| Gene ID | 7057 |
| UniProt ID | P07996 |
| Target Overview | Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp. Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors. |
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Datasheet