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This product is an unconjugated anti-Sulfatase 1 Monoclonal antibody (1A4) generated from the Mouse. This antibody can be used for WB, ELISA, IHC.
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specifications |
|
|---|---|
| Antibody Isotype | IgM, κ |
| Clone | 1A4 |
| Applications | WB; ELISA; IHC |
| Target | Sulfatase 1 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human, Mouse |
| Immunogen | Recombinant human SULF1 protein with GST tag, aa., RTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQCNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG |
| Format | Liquid |
| Buffer | Ascites |
| Storage | Store at -20° C to -80° C. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | Sulfatase 1 |
| Alternative Names | Extracellular Sulfatase Sulf-1; HSulf-1; SULF-1; Sulfatase FP; SULF1 |
| Related Disease | Mesomelia-Synostoses Syndrome; Mesomelia |
| Gene ID | 23213 |
| UniProt ID | Q8IWU6 |
| Target Overview | Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Diminishes HSPG (heparan sulfate proteoglycans) sulfation, inhibits signaling by heparin-dependent growth factors, diminishes proliferation, and facilitates apoptosis in response to exogenous stimulation. |
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Datasheet
