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Mouse Anti-Nitric Oxide Synthase 2 IgM Monoclonal Antibody (NOS-3F7-B11 B5) (CAT#: NGM-103)

This product is an unconjugated anti-Nitric Oxide Synthase 2 Monoclonal antibody (NOS-3F7-B11 B5) generated from the Mouse. This antibody can be used for WB, IF, IHC, IP.

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Antibody Isotype IgM
Clone NOS-3F7-B11 B5
Applications WB; IF; IHC; IP
Target Nitric Oxide Synthase 2
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Human, Mouse, Rat, Bovine
Immunogen Purified bovine bNOS
Format Liquid
Buffer Ascites
Storage Store at -20° C to -80° C. Avoid freeze-thaw cycles.

Target Information

Target Name Nitric Oxide Synthase 2
Alternative Names HEP-NOS; INOS; Nitric Oxide Synthase 2A (Inducible, Hepatocytes); Peptidyl-Cysteine S-Nitrosylase NOS2; Nitric Oxide Synthase Inducible; Inducible NO Synthase; Hepatocyte NOS; Inducible NOS; NOS2A; NOS 2; Nitric Oxide Synthase Macrophage; NOS Type II; NOS2
Related Disease Malaria; Meningioma Familial
Gene ID 4843
UniProt ID P35228
Target Overview Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.
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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.






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