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Mouse Anti-Mouse CD207 IgM Monoclonal Antibody (205C1) [Alexa Fluor® 488] (CAT#: NGM-087)

This product is a conjugated anti-Mouse CD207 Monoclonal antibody (205C1) generated from the Mouse. This antibody can be used for FC.

Please feel free to contact us for a quote and further discussion with our scientists. Datasheets

specifications

Antibody Isotype IgM
Clone 205C1
Applications FC
Target CD207
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Mouse
Immunogen CD207
Format Liquid
Buffer PBS and 50% Glycerol
Storage Store at 4° C in dark. Do not freeze.

Target Information

Target Name CD207
Alternative Names Langerin; CD207 Molecule; CLEC4K; C-Type Lectin Domain Family 4 Member K; Langerhans Cell Specific C-Type Lectin
Related Disease Birbeck Granule Deficiency; Langerhans Cell Histiocytosis
Gene ID 50489
UniProt ID Q9UJ71
Target Overview Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
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KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.

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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

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