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This product is an unconjugated anti-Kinesin 5B Monoclonal antibody (KN-03) generated from the Mouse. This antibody can be used for IF.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | KN-03 |
| Applications | IF |
| Target | Kinesin 5B |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Porcine, Human, Mouse, Rat |
| Immunogen | Enriched fraction of porcine brain kinesin |
| Format | Liquid |
| Buffer | TBS, pH 8.0 |
| Storage | Store at 4° C. |
Target Information |
|
|---|---|
| Target Name | Kinesin 5B |
| Alternative Names | Kinesin Family Member 5B; KNS; Conventional Kinesin Heavy Chain; Ubiquitous Kinesin Heavy Chain; Kinesin-1 Heavy Chain; KNS1; UKHC; Epididymis Secretory Protein Li 61; Kinesin 1; Kinesin Heavy Chain; HEL-S-61; KIF5B; KINH |
| Related Disease | Cerebral Degeneration; Attention Deficit-Hyperactivity Disorder |
| Gene ID | 3799 |
| UniProt ID | P33176 |
| Target Overview | Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. |
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Datasheet
