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This product is an unconjugated anti-Human TIRAP Monoclonal antibody (20D1055.1) generated from the Mouse. This antibody can be used for WB.
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specifications |
|
|---|---|
| Antibody Isotype | IgM, κ |
| Clone | 20D1055.1 |
| Applications | WB |
| Target | TIRAP |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide corresponding to a portion of human TIRAP |
| Format | Liquid |
| Buffer | Ascites with 0.05% BSA |
| Storage | Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | TIRAP |
| Alternative Names | TIR Domain Containing Adaptor Protein; Toll/Interleukin-1 Receptor Domain-Containing Adapter Protein; MyD88 Adapter-Like Protein; Adaptor Protein Wyatt; MyD88-2; Wyatt; Mal; Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein; TIR Domain-Containing Adapter Protein; Toll-Like Receptor Adaptor Protein; Adapter Protein Wyatt; MyD88 Adapter-Like; BACTS1; MAL |
| Related Disease | Bacteremia 1; Malaria |
| Gene ID | 114609 |
| UniProt ID | P58753 |
| Target Overview | Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. |
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Datasheet