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This product is an unconjugated anti-Human TIMM13 Monoclonal antibody (4F4) generated from the Mouse. This antibody can be used for WB, ELISA.
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specifications |
|
|---|---|
| Antibody Isotype | IgM, κ |
| Clone | 4F4 |
| Applications | WB; ELISA |
| Target | TIMM13 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant TIMM13 protein with GST tag, aa., MEGGFGSDFGGSGSGKLDPGLIMEQVKVQIAVANAQELLQRMTDKCFRKCIGKPGGSLDNSEQKCIAMCMDRYMDAWNTVSRAYNSRLQRERANM |
| Format | Liquid |
| Buffer | Ascites |
| Storage | Store at -20° C to -80° C. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | TIMM13 |
| Alternative Names | Translocase of Inner Mitochondrial Membrane 13; Mitochondrial Import Inner Membrane Translocase Subunit Tim13; TIMM13A; TIMM13B; TIM13B; Translocase Of Inner Mitochondrial Membrane 13 (Yeast) Homolog B; Translocase Of Inner Mitochondrial Membrane 13 Homolog (Yeast); Mitochondrial Import Inner Membrane Translocase Subunit Tim13B; Translocase Of Inner Mitochondrial Membrane 13 Homolog; TIM13; Tim13; Ppv1 |
| Related Disease | Mohr-Tranebjaerg Syndrome; Visual Cortex Disease |
| Gene ID | 26517 |
| UniProt ID | Q9Y5L4 |
| Target Overview | Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. |
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Datasheet