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This product is an unconjugated anti-Human SCN5A Monoclonal antibody (4G8:1G7) generated from the Mouse. This antibody can be used for WB, ELISA, FC, IF, IHC, IP, RIA.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | 4G8:1G7 |
| Applications | WB; ELISA; FC; IF; IHC; IP; RIA |
| Target | SCN5A |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Peptide from an extracellular domain of Sodium Voltage-Gated Channel Alpha Subunit 5: VSENIKLGNLSALR |
| Format | Liquid |
| Buffer | PBS |
| Storage | Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | SCN5A |
| Alternative Names | Sodium Voltage-Gated Channel Alpha Subunit 5; HH1; Sodium Channel Voltage-Gated Type V Alpha Subunit; Sodium Channel Protein Cardiac Muscle Subunit Alpha; Voltage-Gated Sodium Channel Subunit Alpha Nav1.5; Sodium Channel Protein Type 5 Subunit Alpha; Nav1.5; CDCD2; CMPD2; PFHB1; HBBD; ICCD; LQT3; SSS1; IVF; Cardiac Tetrodotoxin-Insensitive Voltage-Dependent Sodium Channel Alpha Subunit; Sodium Channel, Voltage-Gated, Type V, Alpha (Long QT Syndrome 3); Sodium Channel, Voltage Gated, Type V Alpha Subunit; Sodium Channel Protein Type V Subunit Alpha; Long QT Syndrome 3; CMD1E; VF1 |
| Related Disease | Sudden Infant Death Syndrome; Long Qt Syndrome 3 |
| Gene ID | 6331 |
| UniProt ID | Q14524 |
| Target Overview | This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
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Datasheet
