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This product is an unconjugated anti-Human RPS14 Monoclonal antibody (2B1) generated from the Mouse. This antibody can be used for WB, ELISA.
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specifications |
|
|---|---|
| Antibody Isotype | IgM, κ |
| Clone | 2B1 |
| Applications | WB; ELISA |
| Target | RPS14 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant human RPS14 protein with GST tag |
| Format | Liquid |
| Buffer | PBS, pH 7.4 |
| Storage | Store at -20° C to -80° C. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | RPS14 |
| Alternative Names | Ribosomal Protein S14; 40S Ribosomal Protein S14; Small Ribosomal Subunit Protein US11; Emetine Resistance; EMTB; S14 |
| Related Disease | Chromosome 5Q Deletion Syndrome; Macrocytic Anemia |
| Gene ID | 6208 |
| UniProt ID | P62263 |
| Target Overview | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. |
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Datasheet