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This product is an unconjugated anti-Human OATP-2 Monoclonal antibody (ESL) generated from the Mouse. This antibody can be used for WB, FC, IHC, IP, IF.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | ESL |
| Applications | WB; FC; IHC; IP; IF |
| Target | OATP-2 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant human Solute carrier organic anion transporter family member 1B1, aa., ESLNKNKHFVPSAGADSETHC |
| Format | Liquid |
| Buffer | Tissue culture supernatant |
| Storage | Store at -20° C to -80° C. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | OATP-2 |
| Alternative Names | Solute Carrier Organic Anion Transporter Family Member 1B1; OATP1B1; OATP-C; LST-1; Solute Carrier Family 21 (Organic Anion Transporter) Member 6; Sodium-Independent Organic Anion-Transporting Polypeptide 2; Liver-Specific Organic Anion Transporter 1; SLC21A6; OATPC; LST1; Solute Carrier Family 21 Member 6; SLCO1B1; HBLRR |
| Related Disease | Hyperbilirubinemia Rotor Type; Gilbert Syndrome |
| Gene ID | 10599 |
| UniProt ID | Q9Y6L6 |
| Target Overview | OATP-2 mediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver. |
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Datasheet
