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This product is a conjugated anti-Human N-Cadherin Monoclonal antibody (691723) generated from the Mouse. This antibody can be used for FC.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | 691723 |
| Applications | FC |
| Target | N-Cadherin |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant mouse N-Cadherin, aa., 160-724 |
| Format | Liquid |
| Buffer | PBS with BSA |
| Storage | Store at 4° C in dark. Do not freeze. |
Target Information |
|
|---|---|
| Target Name | N-Cadherin |
| Alternative Names | Cadherin 2; CDHN; Cadherin 2 Type 1 N-Cadherin (Neuronal); Neural Cadherin; N-Cadherin 2; Cadherin-2; CDw325; CD325; NCAD; Calcium-Dependent Adhesion Protein Neuronal; CD325 Antigen; N-Cadherin 1; ARVD14; ACOGS; CDH2 |
| Related Disease | Agenesis Of Corpus Callosum Cardiac Ocular And Genital Syndrome; Arrhythmogenic Right Ventricular Dysplasia Familial 14 |
| Gene ID | 1000 |
| UniProt ID | P19022 |
| Target Overview | Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. |
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Datasheet
