Mouse Anti-Human IgA2 Monoclonal Antibody (NI25.TA2) (CAT#: NITT-0325-TT6)

This product is an unconjugated/HRP/FITC/Biotin/AP Human IgA2 Monoclonal Antibody (NI25.TA2) gernerated from the Mouse. It is usually applied for ELISA, IHC, ICC, FC, WB.

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specifications

Antibody Isotype IgG1, κ
Clone Monoclonal
Applications ELISA; IHC; ICC; FC; WB
Target IgA2
Host Mouse
Species Reactivity Human
Immunogen Human IgA2
Format Liquid
Buffer PBS
Storage Store at 4°C, protect from light for conjugation.

Target Information

Target Name IgA2
Alternative Names IGHA2; Immunoglobulin heavy constant alpha 2
Gene ID 3494
UniProt ID P01877
Target Overview Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens.
The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Ig alpha is the major immunoglobulin class in body secretions.
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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
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