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This product is a conjugated anti-Human GlcAT-P Monoclonal antibody (TB01) generated from the Mouse. This antibody can be used for WB, FC, IF, IHC.
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specifications |
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Antibody Isotype | IgM |
Clone | TB01 |
Applications | WB; FC; IF; IHC |
Target | GlcAT-P |
Host | Mouse |
Clonality | Monoclonal |
Antibody Type | Primary antibody |
Species Reactivity | Human |
Immunogen | neuroblastoma cell lines |
Format | Liquid |
Buffer | 50mM Sodium Borate |
Storage | Store at 4° C in dark. Do not freeze. |
Target Information |
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Target Name | GlcAT-P |
Alternative Names | Beta-1,3-Glucuronyltransferase 1; Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1; Glucuronosyltransferase P; UDP-GlcUA:Glycoprotein Beta-1,3-Glucuronyltransferase; GLCATP; NK-1; LEU7 Antigen; GlcUAT-P; GLCUATP; B3GAT1; HNK-1; CD57; HNK1; LEU7; NK1 |
Related Disease | Renal Adenoma; Chronic Nk-Cell Lymphocytosis |
Gene ID | 27087 |
UniProt ID | Q9P2W7 |
Target Overview | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
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