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This product is an unconjugated anti-Human Fibronectin Monoclonal antibody (P1F11) generated from the Mouse. This antibody can be used for IF.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | P1F11 |
| Applications | IF |
| Target | Fibronectin |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Fibronectin derived Human plasma |
| Format | Lyophilized |
| Buffer | PBS with Trehalose |
| Storage | Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | Fibronectin |
| Alternative Names | Fibronectin 1; Cold-Insoluble Globulin; CIG; Migration-Stimulating Factor; GFND2; FINC; LETS; MSF; FN; Epididymis Secretory Sperm Binding Protein; SMDCF; ED-B; GFND; FNZ; FN1 |
| Related Disease | Spondylometaphyseal Dysplasia Corner Fracture Type; Glomerulopathy With Fibronectin Deposits 2 |
| Gene ID | 2335 |
| UniProt ID | P02751 |
| Target Overview | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. |
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Datasheet
