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Mouse Anti-Human Fibronectin IgM Monoclonal Antibody (P1F11) (CAT#: NGM-189)

This product is an unconjugated anti-Human Fibronectin Monoclonal antibody (P1F11) generated from the Mouse. This antibody can be used for IF.

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Antibody Isotype IgM
Clone P1F11
Applications IF
Target Fibronectin
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Human
Immunogen Fibronectin derived Human plasma
Format Lyophilized
Buffer PBS with Trehalose
Storage Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles.

Target Information

Target Name Fibronectin
Alternative Names Fibronectin 1; Cold-Insoluble Globulin; CIG; Migration-Stimulating Factor; GFND2; FINC; LETS; MSF; FN; Epididymis Secretory Sperm Binding Protein; SMDCF; ED-B; GFND; FNZ; FN1
Related Disease Spondylometaphyseal Dysplasia Corner Fracture Type; Glomerulopathy With Fibronectin Deposits 2
Gene ID 2335
UniProt ID P02751
Target Overview Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.






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