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This product is an unconjugated anti-Human CD289 Monoclonal antibody (229106) generated from the Mouse. This antibody can be used for FC.
Please feel free to contact us for a quote and further discussion with our scientists. Datasheets
specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | 229106 |
| Applications | FC |
| Target | CD289 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant human Toll Like Receptor 9 |
| Format | Lyophilized |
| Buffer | PBS with Trehalose |
| Storage | Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | CD289 |
| Alternative Names | Toll Like Receptor 9; TLR9 |
| Related Disease | Meningococcal Meningitis; Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Syndrome |
| Gene ID | 54106 |
| UniProt ID | Q9NR96 |
| Target Overview | Key component of innate and adaptive immunity. TLRs control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.
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Datasheet
