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This product is an unconjugated anti-Human CD108 Monoclonal antibody (MEM-150) generated from the Mouse. This antibody can be used for WB, FC, IP.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | MEM-150 |
| Applications | WB; FC; IP |
| Target | CD108 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | HPB-ALL human T cell line |
| Format | Liquid |
| Buffer | TBS |
| Storage | Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | CD108 |
| Alternative Names | Semaphorin-7A; CDw108; JMH blood group antigen; John-Milton-Hargen human blood group Ag; Semaphorin-K1; Sema K1; Semaphorin-L; Sema L; JMH; SEMAL; CDw108; H-SEMA-K1 |
| Related Disease | Blood Group John Milton Hagen System; Chromosome 15Q24 Deletion Syndrome |
| Gene ID | 8482 |
| UniProt ID | O75326 |
| Target Overview | Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.
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Datasheet