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This product is an unconjugated anti-Human CD100 Monoclonal antibody (133-1C6) generated from the Mouse. This antibody can be used for ELISA, FC, IF.
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specifications |
|
|---|---|
| Antibody Isotype | IgM, κ |
| Clone | 133-1C6 |
| Applications | ELISA; FC; IF |
| Target | CD100 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | PHA stimulated human peripheral blood lymphocytes |
| Format | Liquid |
| Buffer | 10 mM PBS with 0.05% BSA |
| Storage | Store at 4° C. |
Target Information |
|
|---|---|
| Target Name | CD100 |
| Alternative Names | Semaphorin 4D; Semaphorin-4D; C9orf164; Coll-4; SEMAJ; BB18; GR3; A8; Chromosome 9 Open Reading Frame 164; CD100 Antigen; M-Sema G; M-Sema-G; FLJ39737; SEMA4D; COLL4 |
| Related Disease | Autoimmune Vasculitis; Osteonecrosis Of The Jaw |
| Gene ID | 10507 |
| UniProt ID | Q92854 |
| Target Overview | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway. |
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Datasheet
