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This product is an unconjugated anti-Human Adrenomedullin Monoclonal antibody (HTA 91a/G2) generated from the Mouse. This antibody can be used for IF, IHC.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | HTA 91a/G2 |
| Applications | IF; IHC |
| Target | Adrenomedullin |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant human adrenomedullin |
| Format | Liquid |
| Buffer | PBS |
| Storage | Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | Adrenomedullin |
| Alternative Names | AM; Pro-Adrenomedullin; Proadrenomedullin N-20 Terminal Peptide; Preproadrenomedullin; PAMP; ADM |
| Related Disease | Pheochromocytoma; Malignant Hypertension |
| Gene ID | 133 |
| UniProt ID | P35318 |
| Target Overview | AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
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Datasheet
