Book a Meeting
Mouse Anti-HSP65 IgM Monoclonal Antibody (3F7) [Alexa Fluor® 647] (CAT#: NGM-249)

This product is a conjugated anti-HSP65 Monoclonal antibody (3F7) generated from the Mouse. This antibody can be used for WB.

Please feel free to contact us for a quote and further discussion with our scientists. Datasheets


Antibody Isotype IgM
Clone 3F7
Applications WB
Target HSP65
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Mycobacterium bovis, Human, Mouse, Rat, Bovine, Cryptospordium, Drosophila, Ecoli, Guinea pig, Hamster
Immunogen Recombinant M. bovis HSP65
Format Liquid
Buffer 50mM Sodium Borate
Storage Store at 4° C in dark. Do not freeze.

Target Information

Target Name HSP65
Alternative Names 60 kDa chaperonin 2; 65 kDa antigen; Antigen A; Cell wall protein A; GroEL protein 2; Heat shock protein 65; Protein Cpn60-2; groL2; groEL-2; groEL2; hsp65
Related Disease Spastic Paraplegia 13 Autosomal Dominant; Leukodystrophy Hypomyelinating 4
Gene ID 45424401
UniProt ID P0A521
Target Overview Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.
  • Customer Reviews
  • Downloadable Resources

Click the button below to contact us or submit your feedback about this product.

!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.

Online Inquiry
For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.






Stay Up To Date

© 2024 Creative Biolabs All Rights Reserved