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This product is an unconjugated anti-F-actin Monoclonal antibody (NH3) generated from the Mouse. This antibody can be used for WB, IHC, FC, ELISA.
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specifications |
|
|---|---|
| Antibody Isotype | IgM |
| Clone | NH3 |
| Applications | WB; IHC; FC; ELISA |
| Target | F-actin |
| Epitope | This antibody recognizes an epitope between residues 120 and 226 of the molecule. |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human, Mouse, Rabbit, Rat |
| Immunogen | Human monocytes and U937 cell line |
| Format | Liquid |
| Buffer | PBS |
| Storage | Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | F-actin |
| Alternative Names | Actin Beta; Filamentous actin; Actin Cytoplasmic 1; PS1TP5-Binding Protein; Beta Cytoskeletal Actin; I(2)-Actin; Beta-Actin; PS1TP5BP1; Β-Actin; BRWS1; ACTB |
| Related Disease | Dystonia Juvenile-Onset; Baraitser-Winter Syndrome 1 |
| Gene ID | 60 |
| UniProt ID | P60709 |
| Target Overview | Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. |
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Datasheet