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Mouse Anti-CD55 IgM Monoclonal Antibody (MEM-118) (CAT#: NGM-111)

This product is an unconjugated anti-CD55 Monoclonal antibody (MEM-118) generated from the Mouse. This antibody can be used for FC, IHC, IP.

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Antibody Isotype IgM
Clone MEM-118
Applications FC; IHC; IP
Target CD55
Epitope This antibody recognizes an epitope in SCR4 domain of CD55.
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Human, Primate
Immunogen HPB-ALL human T cell line
Format Liquid
Buffer TBS, pH 8.0
Storage Store at 4° C.

Target Information

Target Name CD55
Alternative Names CD55 Molecule (Cromer Blood Group); CD55 Molecule, Decay Accelerating Factor For Complement (Cromer Blood Group); Complement Decay-Accelerating Factor; CD55 Antigen; CROM; DAF; TC; Cromer Blood Group Antigen; Rh Blood Group D Antigen; CHAPLE
Related Disease Complement Hyperactivation Angiopathic Thrombosis And Protein-Losing Enteropathy; Blood Group Cromer System
Gene ID 1604
UniProt ID P08174
Target Overview This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. It acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5, Human enterovirus 70 and D68, Human echoviruses 6, 7, 11, 12, 20 and 21.
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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.






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