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This product is a His-Tagged anti-c-myc epitope tag Monoclonal Antibody (NGE30-TT) gernerated from the human. This antibody can be used for applications: IHC-F; IHC-P; IP; WB; IF.
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specifications |
|
|---|---|
| Antibody Isotype | IgE |
| Clone | NGE30-TT |
| Applications | IHC-F; IHC-P; IP; WB; IF |
| Target | C-Myc |
| Host | Human |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide corresponding to aa 408-439 from C-terminus of human c-myc. |
| Format | Liquid |
| Buffer | PBS |
| Storage | Store at 4°C for short-term and -20°C for long-term. Avoid repeated freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | C-Myc |
| Alternative Names | MYC Proto-Oncogene, BHLH Transcription Factor; BHLHe39; V-Myc Avian Myelocytomatosis Viral Oncogene Homolog; Class E Basic Helix-Loop-Helix Protein 39; Myc Proto-Oncogene Protein; Transcription Factor P64; Proto-Oncogene C-Myc; MYC; MYCC; Myc-Related Translation/Localization Regulatory Factor; Avian Myelocytomatosis Viral Oncogene Homolog; V-Myc Myelocytomatosis Viral Oncogene Homolog; BHLHE39; MRTL |
| Related Disease | Burkitt Lymphoma; High Grade B-Cell Lymphoma With Myc And/ Or Bcl2 And/Or Bcl6 Rearrangement |
| Gene ID | 4609 |
| UniProt ID | P01106 |
| Target Overview | Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. |
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Datasheet