IgM, also known as immunoglobulin M, is the largest antibody that is produced by the immune system of vertebrates. It can attack against a wide variety of antigens and take part in many steps of the primary and adaptive humoral immune response. It is noteworthy that IgM can more effectively activate the complement system than any other isotypes, contributing to a number of cytotoxic and cytolytic reactions. In structural, the IgM monomer consists of two identical heavy chains (μ) and two light chains (κ or λ), and each chain can be divided into two domains, a variable (V) domain, and four different constant (C) domains. The variable domain of IgM is usually used for binding to antigens, and then the constant domains of IgM can interact with phagocytic cells and the complement system. Meanwhile, recent studies have revealed that recombinant IgM antibodies can be regarded as a therapeutic agent in cancer immunotherapy and has been performed related to a number of carcinomas, such as epithelial ovarian cancer (EOC), breast cancer, as well as lung cancer.
Therapeutic antibodies play an important role in a number of disease treatments, especially in cancer therapy. As a service provider in non-IgG antibody development, Creative Biolabs is dedicated to offering a wide spectrum of in vitro diagnostic (IVD) antibody products and services to illustrate antibody bioactivity and mechanism of action. We are specialized in designing and manufacturing high-quality recombinant IgM antibodies with different formats to satisfy the specific requirement at the most competitive price.
For more detailed information, please feel free to contact us or directly sent us an inquiry.
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
|Catalog#||Product Name||Antibody Isotype||Host||Applications||Species Reactivity||Inquiry|
|NGM-101||Mouse Anti-Basophils Monoclonal Antibody (212H6.16) [Alexa Fluor® 546]||IgM||Mouse||IF; IHC||Human, Canine||Inquiry Datasheet|
|NGM-102||Mouse Anti-Basophils Monoclonal Antibody (212H6.16) [Alexa Fluor® 647]||IgM||Mouse||FC||Human, Canine||Inquiry Datasheet|
|NGM-103||Mouse Anti-Nitric Oxide Synthase 2 Monoclonal Antibody (NOS-3F7-B11 B5)||IgM||Mouse||WB; IF; IHC; IP||Human, Mouse, Rat, Bovine||Inquiry Datasheet|
|NGM-104||Mouse Anti-DNA Monoclonal Antibody (AC-30-10)||IgM||Mouse||WB; IF; IHC||All species||Inquiry Datasheet|
|NGM-105||Mouse Anti-FcγRIIIa Monoclonal Antibody (MEM-168)||IgM||Mouse||FC||Human, Porcine, Primate||Inquiry Datasheet|
|NGM-106||Mouse Anti-Human SCAI Monoclonal Antibody (7-A4)||IgM||Mouse||WB; IF; IHC||Human||Inquiry Datasheet|
|NGM-107||Mouse Anti-Protocadherin Fat 1 Monoclonal Antibody (FAT-1 3D7/1)||IgM||Mouse||WB; ELISA; IF; IHC||Drosophilia, Primate||Inquiry Datasheet|
|NGM-108||Mouse Anti-Replication Protein A2 Monoclonal Antibody (MA34)||IgM||Mouse||WB; IF; IHC||Human, Rat||Inquiry Datasheet|
|NGM-109||Mouse Anti-Nuclear Pore-O-Linked Glycoprotein Monoclonal Antibody (RL1)||IgM||Mouse||WB; IHC; IP; IF||Human, Mouse, Rat, Xenopus, Yeast||Inquiry Datasheet|
|NGM-110||Mouse Anti-Fibroblast Monoclonal Antibody (1B10)||IgM||Mouse||FC; IHC||Human, Mouse||Inquiry Datasheet|
|NGM-111||Mouse Anti-CD55 Monoclonal Antibody (MEM-118)||IgM||Mouse||FC; IHC; IP||Human, Primate||Inquiry Datasheet|
|NGM-112||Mouse Anti-Calpain 1 Monoclonal Antibody (2A2)||IgM||Mouse||FC; IF; IHC||Human, Mouse, Rat||Inquiry Datasheet|
|NGM-113||Rat Anti-Mouse ACKR3 Monoclonal Antibody (734110)||IgM||Rat||FC; ELISA||Mouse||Inquiry Datasheet|
|NGM-114||Rat Anti-Mouse ACKR3 Monoclonal Antibody (734110) [Alexa Fluor® 350]||IgM||Rat||FC||Mouse||Inquiry Datasheet|
|NGM-115||Rat Anti-Mouse ACKR3 Monoclonal Antibody (734110) [Alexa Fluor® 405]||IgM||Rat||FC||Mouse||Inquiry Datasheet|
|NGM-116||Rat Anti-Mouse ACKR3 Monoclonal Antibody (734110) [Alexa Fluor® 488]||IgM||Rat||FC||Mouse||Inquiry Datasheet|
|NGM-117||Rat Anti-Mouse ACKR3 Monoclonal Antibody (734110) [Alexa Fluor® 594]||IgM||Rat||FC||Mouse||Inquiry Datasheet|
|NGM-118||Rat Anti-Mouse ACKR3 Monoclonal Antibody (734110) [Alexa Fluor® 647]||IgM||Rat||FC||Mouse||Inquiry Datasheet|
|NGM-119||Rat Anti-Mouse ACKR3 Monoclonal Antibody (734110) [Alexa Fluor® 700]||IgM||Rat||FC||Mouse||Inquiry Datasheet|
|NGM-120||Rat Anti-Mouse ACKR3 Monoclonal Antibody (734110) [Alexa Fluor® 750]||IgM||Rat||FC||Mouse||Inquiry Datasheet|
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