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IgM

IgM Antibodies-Creative Biolabs.

IgM, also known as immunoglobulin M, is the largest antibody that is produced by the immune system of vertebrates. It can attack against a wide variety of antigens and take part in many steps of the primary and adaptive humoral immune response. It is noteworthy that IgM can more effectively activate the complement system than any other isotypes, contributing to a number of cytotoxic and cytolytic reactions. In structural, the IgM monomer consists of two identical heavy chains (μ) and two light chains (κ or λ), and each chain can be divided into two domains, a variable (V) domain, and four different constant (C) domains. The variable domain of IgM is usually used for binding to antigens, and then the constant domains of IgM can interact with phagocytic cells and the complement system. Meanwhile, recent studies have revealed that recombinant IgM antibodies can be regarded as a therapeutic agent in cancer immunotherapy and has been performed related to a number of carcinomas, such as epithelial ovarian cancer (EOC), breast cancer, as well as lung cancer.

Therapeutic antibodies play an important role in a number of disease treatments, especially in cancer therapy. As a service provider in non-IgG antibody development, Creative Biolabs is dedicated to offering a wide spectrum of in vitro diagnostic (IVD) antibody products and services to illustrate antibody bioactivity and mechanism of action. We are specialized in designing and manufacturing high-quality recombinant IgM antibodies with different formats to satisfy the specific requirement at the most competitive price.

For more detailed information, please feel free to contact us or directly sent us an inquiry.

KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

Catalog# Product Name Antibody Isotype Host Applications Species Reactivity Inquiry
NGM-201 Mouse Anti-Mouse Toll-like receptor 12 Monoclonal Antibody (15F1215) IgM Mouse WB Mouse Inquiry Datasheet
NGM-202 Mouse Anti-Rat Beta-2-Microglobulin Monoclonal Antibody (747502) IgM Mouse FC; ELISA Rat Inquiry Datasheet
NGM-203 Mouse Anti-Rat Beta-2-Microglobulin Monoclonal Antibody (747502) [Alexa Fluor® 350] IgM Mouse FC Rat Inquiry Datasheet
NGM-204 Mouse Anti-Rat Beta-2-Microglobulin Monoclonal Antibody (747502) [Alexa Fluor® 405] IgM Mouse FC Rat Inquiry Datasheet
NGM-205 Mouse Anti-Rat Beta-2-Microglobulin Monoclonal Antibody (747502) [Alexa Fluor® 594] IgM Mouse FC Rat Inquiry Datasheet
NGM-206 Mouse Anti-Rat Beta-2-Microglobulin Monoclonal Antibody (747502) [Alexa Fluor® 647] IgM Mouse FC Rat Inquiry Datasheet
NGM-207 Mouse Anti-Rat Beta-2-Microglobulin Monoclonal Antibody (747502) [Alexa Fluor® 700] IgM Mouse FC Rat Inquiry Datasheet
NGM-208 Mouse Anti-Rat Beta-2-Microglobulin Monoclonal Antibody (747502) [Alexa Fluor® 750] IgM Mouse FC Rat Inquiry Datasheet
NGM-209 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-210 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) [PE] IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-211 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) [Alexa Fluor® 350] IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-212 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) [Alexa Fluor® 405] IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-213 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) [Alexa Fluor® 488] IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-214 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) [Alexa Fluor® 594] IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-215 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) [Alexa Fluor® 647] IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-216 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) [Alexa Fluor® 700] IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-217 Mouse Anti-Human ACKR4 Monoclonal Antibody (674144) [Alexa Fluor® 750] IgM Mouse FC; ELISA Human Inquiry Datasheet
NGM-218 Mouse Anti-TGF-α Monoclonal Antibody (TG86 + P/T1) IgM Mouse FC; IF; IHC Human, Rabbit, Zebrafish Inquiry Datasheet
NGM-219 Mouse Anti-TGF-α Monoclonal Antibody (TG86 + P/T1) [FITC] IgM Mouse FC; IF; IHC Human, Rabbit, Zebrafish Inquiry Datasheet
NGM-220 Mouse Anti-Human Cadherin 2 Monoclonal Antibody (691701) IgM Mouse FC; ELISA Human Inquiry Datasheet

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