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This product is an unconjugated anti-PLOD2 monoclonal antibody gernerated from the mouse. This antibody can be used for applications: Western Blotting, Immunohistochemistry, ELISA.
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specifications |
|
|---|---|
| Antibody Isotype | IgA |
| Clone | 1H9E1 |
| Applications | WB; IHC; ELISA |
| Target | PLOD2 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | PLOD2 fusion protein |
| Format | Liquid |
| Buffer | PBS with 50% glycerol pH 7.3 |
| Storage | Store at -20°C. |
Target Information |
|
|---|---|
| Target Name | PLOD2 |
| Alternative Names | Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 2; LH2; Procollagen-Lysine 5-Dioxygenase; Lysyl Hydroxylase 2; Lysyl Hydroxlase 2; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase (Lysine Hydroxylase) 2; Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 2; Telopeptide Lysyl Hydroxylase; Lysine Hydroxylase 2; BRKS2; TLH |
| Related Disease | Bruck Syndrome 2; Bruck Syndrome |
| Gene ID | 5352 |
| UniProt ID | O00469 |
| Target Overview | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. PLOD2,also named as LH2, forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. It is a potential novel prognostic factor for HCC patients following surgery. Among the PLOD genes, PLOD2 contributes to cancer prognosis and angiogenesis. Several authors have reported that PLOD2 expression might provide prognostic information about malignant tumours such as glioblastoma. PLOD2 expression is a useful biomarker for the effects of antiangiogenic treatment for malignancy.(PMID:22098155). It has 2 isoforms produced by alternative splicing and seven glycosylation sites. |
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Datasheet
