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This product is an unconjugated anti-human WW and C2 Domain Containing 1 (WWC1) monoclonal antibody gernerated from the mouse. This antibody can be used for applications: ELISA, Immunofluorescence, Western Blotting.
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specifications |
|
|---|---|
| Antibody Isotype | IgA, κ |
| Clone | 7D11 |
| Applications | ELISA; IF; WB |
| Target | WWC1 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | KIBRA-GST tagged partial recombinant protein |
| Format | Lyophilized |
| Buffer | Tris 0,1M, glycine 0,1M, sucrose 2 % |
| Storage | Store at 4°C for short-term and -20°C for long-term. Avoid repeated freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | WWC1 |
| Alternative Names | WW And C2 Domain Containing 1; KIBRA; Protein Phosphatase 1, Regulatory Subunit 168; WW, C2 And Coiled-Coil Domain Containing 1; Kidney And Brain Protein; HBeAg-Binding Protein 3; Protein KIBRA; WW Domain-Containing Protein 1; Protein WWC1; MEMRYQTL; HBEBP36; HBEBP3 |
| Related Disease | Memory Quantitative Trait Locus; Wilson-Turner X-Linked Mental Retardation Syndrome |
| Gene ID | 23286 |
| UniProt ID | Q8IX03 |
| Target Overview | Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance. |
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Datasheet
