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Anti-Human WW and C2 Domain Containing 1 (WWC1) IgA Monoclonal Antibody (7D11) (CAT#: NGA-048)

This product is an unconjugated anti-human WW and C2 Domain Containing 1 (WWC1) monoclonal antibody gernerated from the mouse. This antibody can be used for applications: ELISA, Immunofluorescence, Western Blotting.

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specifications

Antibody Isotype IgA, κ
Clone 7D11
Applications ELISA; IF; WB
Target WWC1
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Human
Immunogen KIBRA-GST tagged partial recombinant protein
Format Lyophilized
Buffer Tris 0,1M, glycine 0,1M, sucrose 2 %
Storage Store at 4°C for short-term and -20°C for long-term. Avoid repeated freeze-thaw cycles.

Target Information

Target Name WWC1
Alternative Names WW And C2 Domain Containing 1; KIBRA; Protein Phosphatase 1, Regulatory Subunit 168; WW, C2 And Coiled-Coil Domain Containing 1; Kidney And Brain Protein; HBeAg-Binding Protein 3; Protein KIBRA; WW Domain-Containing Protein 1; Protein WWC1; MEMRYQTL; HBEBP36; HBEBP3
Related Disease Memory Quantitative Trait Locus; Wilson-Turner X-Linked Mental Retardation Syndrome
Gene ID 23286
UniProt ID Q8IX03
Target Overview Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.
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KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.

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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

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