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This product is an unconjugated anti-human STC2 monoclonal antibody gernerated from the mouse. This antibody can be used for applications: ELISA, Western Blotting.
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specifications |
|
|---|---|
| Antibody Isotype | IgA, κ |
| Clone | 339CT13.2.6 |
| Applications | ELISA; WB |
| Target | Stanniocalcin-2 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant peptide corresponding to human STC2 |
| Format | Liquid |
| Buffer | PBS, pH 7.2 |
| Storage | Store at 4°C for short-term and -20°C for long-term. Avoid repeated freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | Stanniocalcin-2 |
| Alternative Names | STC-2; Stanniocalcin-related protein; STC-related protein; STCRP |
| Related Disease | Renal Cell Carcinoma Nonpapillary |
| Gene ID | 8614 |
| UniProt ID | O76061 |
| Target Overview | This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. |
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Datasheet
