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This product is an unconjugated anti-human Cytochrome C monoclonal antibody gernerated from the mouse. This antibody can be used for applications: Western Blotting, Immunohistochemistry.
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specifications |
|
|---|---|
| Antibody Isotype | IgA |
| Clone | GT577 |
| Applications | WB; IHC |
| Target | Cytochrome C |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant human Cytochrome C protein |
| Format | Liquid |
| Buffer | PBS |
| Storage | Store at 4°C for short-term and -20°C for long-term. Avoid repeated freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | Cytochrome C |
| Alternative Names | Cytochrome C Somatic; CYC; HCS; THC4; CYCS |
| Related Disease | Thrombocytopenia 4; Autosomal Thrombocytopenia With Normal Platelets |
| Gene ID | 54205 |
| UniProt ID | P99999 |
| Target Overview | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
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Datasheet