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This product is an unconjugated anti-Cas9 monoclonal antibody gernerated from the mouse. This antibody can be used for applications: Western Blotting, ELISA.
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specifications |
|
|---|---|
| Antibody Isotype | IgA |
| Clone | NGA07-TT |
| Applications | WB; ELISA |
| Target | Cas9CRISPR-associated endonuclease Cas9/Csn1 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Streptococcus pyogenes |
| Immunogen | Recombinant fragment corresponding to Cas9 endonuclease from Streptococcus pyogenes. |
| Format | Liquid |
| Buffer | PBS, pH 7.4 |
| Storage | Store at 4°C for short-term and -20°C for long-term. Avoid repeated freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | Cas9CRISPR-associated endonuclease Cas9/Csn1 |
| Alternative Names | SpCas9; SpyCas9 |
| Related Disease | Immunodeficiency |
| Gene ID | 46806597 |
| UniProt ID | Q99ZW2 |
| Target Overview | Cas9, an essential RNA-guided DNA endonuclease observed originally in Streptococcus pyogene among other bacteria and archaea and a component of an adaptive microbial immune system that provides acquired immunity against foreign viruses and plasmids. Cas9 endonuclease is used to cleave double-stranded DNA directed by a short engineered guide-RNA (gRNA), leading to site-directed double strand breaks (DSB) in DNA submstrate. Thus, the CRISPR Cas9 system (clustered regularly interspaced short palindromic repeat CRISPR-associated protein 9) is the latest RNA-guided, endonuclease tool in genome editing which allows for very specific genomic disruption and replacement. |
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
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Datasheet