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IgM

IgM Antibodies-Creative Biolabs.

IgM, also known as immunoglobulin M, is the largest antibody that is produced by the immune system of vertebrates. It can attack against a wide variety of antigens and take part in many steps of the primary and adaptive humoral immune response. It is noteworthy that IgM can more effectively activate the complement system than any other isotypes, contributing to a number of cytotoxic and cytolytic reactions. In structural, the IgM monomer consists of two identical heavy chains (μ) and two light chains (κ or λ), and each chain can be divided into two domains, a variable (V) domain, and four different constant (C) domains. The variable domain of IgM is usually used for binding to antigens, and then the constant domains of IgM can interact with phagocytic cells and the complement system. Meanwhile, recent studies have revealed that recombinant IgM antibodies can be regarded as a therapeutic agent in cancer immunotherapy and has been performed related to a number of carcinomas, such as epithelial ovarian cancer (EOC), breast cancer, as well as lung cancer.

Therapeutic antibodies play an important role in a number of disease treatments, especially in cancer therapy. As a service provider in non-IgG antibody development, Creative Biolabs is dedicated to offering a wide spectrum of in vitro diagnostic (IVD) antibody products and services to illustrate antibody bioactivity and mechanism of action. We are specialized in designing and manufacturing high-quality recombinant IgM antibodies with different formats to satisfy the specific requirement at the most competitive price.

For more detailed information, please feel free to contact us or directly sent us an inquiry.

KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

Catalog# Product Name Antibody Isotype Host Applications Species Reactivity Inquiry
NGM-401 Mouse Anti-Human S100A9 Monoclonal Antibody (MRP14/840) IgM, κ Mouse FC; IF; IHC Human Inquiry Datasheet
NGM-402 Mouse Anti-Human GM2 Ganglioside Monoclonal Antibody (L55-81) IgM, κ Mouse ELISA; Funcs; IF; IHC; Depletion Human Inquiry Datasheet
NGM-403 Mouse Anti-Piccolo Monoclonal Antibody (4G3.3) IgM, κ Mouse WB; IHC Mouse, Rat Inquiry Datasheet
NGM-404 Mouse Anti-Metallothionein-3 Monoclonal Antibody (3E8) IgM, κ Mouse WB; ELISA; IF Human, Rat Inquiry Datasheet
NGM-405 Mouse Anti-F-actin Monoclonal Antibody (NH3) IgM Mouse WB; IHC; FC; ELISA Human, Mouse, Rabbit, Rat Inquiry Datasheet
NGM-406 Mouse Anti-Human HLA-B Monoclonal Antibody (EP-4) IgM, κ Mouse FC; IF Human Inquiry Datasheet
NGM-407 Mouse Anti-Human CD26 Monoclonal Antibody (134-2C2) IgM, κ Mouse FC; IF; IHC Human Inquiry Datasheet
NGM-408 Mouse Anti-Human CD1b Monoclonal Antibody (100-1A5) IgM, κ Mouse FC; Func; IF Human Inquiry Datasheet
NGM-409 Human Anti-Human desmosome/hemidesmosome Monoclonal Antibody (F12) IgM, κ Human EM; FC; IF Human Inquiry Datasheet
NGM-410 Mouse Anti-RAB5A Monoclonal Antibody (5D1) IgM, κ Mouse WB; ELISA Human, Mouse Inquiry Datasheet
NGM-411 Mouse Anti-Mouse HLA-DRB1 Monoclonal Antibody (25-9-3) IgM, κ Mouse FC; IHC Mouse Inquiry Datasheet
NGM-412 Mouse Anti-Chicken CD45 Monoclonal Antibody (LT40) IgM Mouse FC; IHC; IP; IF Chicken Inquiry Datasheet
NGM-413 Mouse Anti-Chicken CD45 Monoclonal Antibody (LT40) [PE] IgM Mouse FC Chicken Inquiry Datasheet
NGM-414 Mouse Anti-Chicken CD45 Monoclonal Antibody (LT40) [PE-Cyanine5] IgM Mouse FC Chicken Inquiry Datasheet
NGM-415 Mouse Anti-Chicken CD45 Monoclonal Antibody (LT40) [FITC] IgM Mouse IHC; FC; IF Chicken Inquiry Datasheet
NGM-416 Mouse Anti-Chicken CD45 Monoclonal Antibody (LT40) [Biotin] IgM Mouse IHC; FC; IF Chicken Inquiry Datasheet
NGM-417 Mouse Anti-Chicken CD45 Monoclonal Antibody (LT40) [APC] IgM Mouse FC Chicken Inquiry Datasheet
NGM-418 Rat Anti-Mouse CD45 Monoclonal Antibody (GL24) IgM, κ Rat FC; IP Mouse Inquiry Datasheet
NGM-419 Mouse Anti-E. coli Monoclonal Antibody (9.88) IgM, κ Mouse ELISA; IF E. coli Inquiry Datasheet
NGM-420 Mouse Anti-Human TIMM13 Monoclonal Antibody (4F4) IgM, κ Mouse WB; ELISA Human Inquiry Datasheet

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