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IgM

IgM Antibodies-Creative Biolabs.

IgM, also known as immunoglobulin M, is the largest antibody that is produced by the immune system of vertebrates. It can attack against a wide variety of antigens and take part in many steps of the primary and adaptive humoral immune response. It is noteworthy that IgM can more effectively activate the complement system than any other isotypes, contributing to a number of cytotoxic and cytolytic reactions. In structural, the IgM monomer consists of two identical heavy chains (μ) and two light chains (κ or λ), and each chain can be divided into two domains, a variable (V) domain, and four different constant (C) domains. The variable domain of IgM is usually used for binding to antigens, and then the constant domains of IgM can interact with phagocytic cells and the complement system. Meanwhile, recent studies have revealed that recombinant IgM antibodies can be regarded as a therapeutic agent in cancer immunotherapy and has been performed related to a number of carcinomas, such as epithelial ovarian cancer (EOC), breast cancer, as well as lung cancer.

Therapeutic antibodies play an important role in a number of disease treatments, especially in cancer therapy. As a service provider in non-IgG antibody development, Creative Biolabs is dedicated to offering a wide spectrum of in vitro diagnostic (IVD) antibody products and services to illustrate antibody bioactivity and mechanism of action. We are specialized in designing and manufacturing high-quality recombinant IgM antibodies with different formats to satisfy the specific requirement at the most competitive price.

For more detailed information, please feel free to contact us or directly sent us an inquiry.

KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

Catalog# Product Name Antibody Isotype Host Applications Species Reactivity Inquiry
NGM-361 Rat Anti-Mouse MIF Monoclonal Antibody (811409) [Alexa Fluor® 750] IgM Rat FC Mouse Inquiry Datasheet
NGM-362 Mouse Anti-Actin Monoclonal Antibody (mAbGEa) IgM, κ Mouse WB; ELISA; FC; IF; IHC Human, Mouse, Rat, Zebrafish, Yeast, Sheep, Drosophila, Bovine, Pig, Xenopus, Plant, Bacteria Inquiry Datasheet
NGM-363 Rat Anti-CD162 Monoclonal Antibody (HECA-452) IgM, κ Rat WB; ELISA; FC; IF; IHC Human, Mouse Inquiry Datasheet
NGM-364 Mouse Anti-Human CD67 Monoclonal Antibody (G10F5) IgM, κ Mouse FC; IHC; IF Human Inquiry Datasheet
NGM-365 Mouse Anti-LASS2 Monoclonal Antibody (1A6) IgM, κ Mouse WB; ELISA; IHC Human, Mouse Inquiry Datasheet
NGM-366 Mouse Anti-TGF-α Monoclonal Antibody (SPM542) IgM, κ Mouse WB; FC; IF; IHC Human, Rabbit, Zebrafish Inquiry Datasheet
NGM-367 Mouse Anti-TGF-α Monoclonal Antibody (SPM542) [FITC] IgM, κ Mouse FC; IF; IHC Human, Rabbit, Zebrafish Inquiry Datasheet
NGM-368 Mouse Anti-TGF-α Monoclonal Antibody (SPM542) [Alexa Fluor® 350] IgM, κ Mouse WB; FC; IF; IHC Human, Rabbit, Zebrafish Inquiry Datasheet
NGM-369 Mouse Anti-TGF-α Monoclonal Antibody (SPM542) [Alexa Fluor® 532] IgM, κ Mouse WB; FC; IF; IHC Human, Rabbit, Zebrafish Inquiry Datasheet
NGM-370 Mouse Anti-TGF-α Monoclonal Antibody (SPM542) [Alexa Fluor® 594] IgM, κ Mouse WB; FC; IF; IHC Human, Rabbit, Zebrafish Inquiry Datasheet
NGM-371 Mouse Anti-TGF-α Monoclonal Antibody (SPM542) [Alexa Fluor® 750] IgM, κ Mouse WB; FC; IF; IHC Human, Rabbit, Zebrafish Inquiry Datasheet
NGM-372 Mouse Anti-TGF-α Monoclonal Antibody (TNFA/1172) IgM, κ Mouse FC; IF; IHC Human, Rat Inquiry Datasheet
NGM-373 Mouse Anti-TGF-α Monoclonal Antibody (4C6-H8) IgM, κ Mouse FC; IF; IHC Human, Mouse, Rat, Rabbit, Caninr, Feline, Zebrafish Inquiry Datasheet
NGM-374 Mouse Anti-TGF-α Monoclonal Antibody (TNF706) IgM, κ Mouse IF; IHC Human, Mouse, Rat, Rabbit, Caninr, Feline, Zebrafish Inquiry Datasheet
NGM-375 Mouse Anti-Thomsen-Friedenreich antigen Monoclonal Antibody (SPM320) IgM, κ Mouse FC; IF; IHC Human, Mouse, Rat Inquiry Datasheet
NGM-376 Mouse Anti-Prostasin Monoclonal Antibody (3C4) IgM, κ Mouse WB; ELISA; IP Human, Mouse, Rat Inquiry Datasheet
NGM-377 Mouse Anti-Sulfatase 1 Monoclonal Antibody (1A4) IgM, κ Mouse WB; ELISA; IHC Human, Mouse Inquiry Datasheet
NGM-378 Mouse Anti-Human TIRAP Monoclonal Antibody (20D1055.1) IgM, κ Mouse WB Human Inquiry Datasheet
NGM-379 Mouse Anti-Human Caspase-2 Monoclonal Antibody (18E809.3) IgM, κ Mouse WB Human Inquiry Datasheet
NGM-380 Mouse Anti-Human CD41/CD61 Monoclonal Antibody (PAC-1) IgM, κ Mouse FC; IF; IP Human Inquiry Datasheet

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