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IgE

IgE Antibodies-Creative Biolabs.

IgE antibody, also known as immunoglobulin E, is the least abundant isotype that only presents in mammals. IgE antibody is similar to IgG antibody in structure, which is both Y-shaped. Generally, IgE antibodies are composed of two identical light chains and heavy chains (ε chain), where each light chain contains 1 variable domain and 1 constant domain while each heavy chain contains 1 variable domain and 4 constant domains. IgE is a heavily glycosylated antibody having a total of 6 N-linked glycosylation sites, of which glycans make up more than 10% of its molecular mass.

In the human body, IgE antibody is mainly produced by plasma cells of respiratory and digestive tract mucosa, which is at an extremely low level in the circulation of healthy people but is significantly elevated in allergic individuals. By binding to Fcε receptors on the surface of mast cells, basophils, eosinophils, etc., IgE antibody acts an essential role in inducing the allergic immune response (type I hypersensitivity) once exposed to allergens. Recently, increasing studies have pointed out that IgE antibodies exhibit potential natural roles in cancer immune surveillance, which prompts us to actively devote ourselves to the research and development of IgE antibody.

As a leading antibody products and services provider, Creative Biolabs is professional and experimental in providing global clients with high-quality IgE antibodies for diagnostic or therapeutic applications. Our specialized scientists are confident in offering the best IgE antibodies upon request. Welcome to inquire or contact us for more detailed information.

KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

Catalog# Product Name Antibody Isotype Host Applications Species Reactivity Inquiry
NGE-061 Human anti-Fluorescein Monoclonal Antibody (NGE33-TT) IgE, κ Human negative control; WB; FC Inquiry Datasheet
NGE-062 Human anti-Fluorescein Monoclonal Antibody (NGE33-TT)-His Tagged IgE, κ Human negative control; WB; FC Inquiry Datasheet
NGE-063 Human anti-4-hydroxy-3-nitrophenyl acetyl Monoclonal Antibody (NGE34-TT) IgE, λ Human negative control; WB; FC Inquiry Datasheet
NGE-064 Recombinant anti-4-hydroxy-3-nitrophenyl acetyl Monoclonal Antibody (NGE35-TT) IgE Human Cells ELISA Inquiry Datasheet
NGE-065 Mouse anti-4-hydroxy-3-nitrophenyl acetyl Monoclonal Antibody (NGE36-TT) IgE Mouse ELISA Inquiry Datasheet
NGE-066 Goat anti-IgE (Fc) Polyclonal Antibody IgE Goat ELISA Human Inquiry Datasheet

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