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Mouse Anti-Thyroglobulin IgM Monoclonal Antibody (12G9) (CAT#: NGM-307)

This product is an unconjugated anti-Thyroglobulin Monoclonal antibody (12G9) generated from the Mouse. This antibody can be used for ELISA.

Please feel free to contact us for a quote and further discussion with our scientists. Datasheets

specifications

Antibody Isotype IgM
Clone 12G9
Applications ELISA
Target Thyroglobulin
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Human, Mouse, Rat, Porcine, Bovine, Canine, Feline
Immunogen Thyroglobulin from human thyroid gland
Format Liquid
Buffer PBS, pH 7.4
Storage Store at 4° C.

Target Information

Target Name Thyroglobulin
Alternative Names AITD3; TGN; TG; Tg
Related Disease Thyroid Dyshormonogenesis 3; Autoimmune Thyroid Disease 3
Gene ID 7038
UniProt ID P01266
Target Overview Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules.
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KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.

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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

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