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Mouse Anti-Porcine PTPRC Monoclonal Antibody (MIL15)

Mouse Anti-Porcine PTPRC Monoclonal Antibody (MIL15) (CAT#: NGM-287)

This product is an unconjugated anti-Porcine PTPRC Monoclonal antibody (MIL15) generated from the Mouse. This antibody can be used for FC, IHC.

Please feel free to contact us for a quote and further discussion with our scientists. Datasheets

specifications
Antibody Isotype IgM
Clone MIL15
Applications FC; IHC
Target PTPRC
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
species Reactivity Porcine
Immunogen Cells isolated from porcine mesenteric lymph node
Format Liquid
Buffer Tissue culture supernatant
Storage Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles.
Target Information
Target Name PTPRC
Alternative Names Protein Tyrosine Phosphatase Receptor Type C; T200; Receptor-Type Tyrosine-Protein Phosphatase C; CD45 Antigen; GP180; CD45; LCA; Protein Tyrosine Phosphatase Receptor Type C Polypeptide; T200 Leukocyte Common Antigen; Leukocyte Common Antigen; T200 Glycoprotein; CD45R; B220; LY5
Related Disease Severe Combined Immunodeficiency Autosomal Recessive T Cell-Negative B Cell-Positive Nk Cell-Positive; Hepatitis C Virus
Gene ID 100522631
UniProt ID A0A287A9D0
Target Overview Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. It acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.

KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.

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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

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