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Mouse Anti-Human N-Cadherin IgM Monoclonal Antibody (691723) [Alexa Fluor® 647] (CAT#: NGM-344)

This product is a conjugated anti-Human N-Cadherin Monoclonal antibody (691723) generated from the Mouse. This antibody can be used for FC.

Please feel free to contact us for a quote and further discussion with our scientists. Datasheets

specifications

Antibody Isotype IgM
Clone 691723
Applications FC
Target N-Cadherin
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Human
Immunogen Recombinant mouse N-Cadherin, aa., 160-724
Format Liquid
Buffer PBS with BSA
Storage Store at 4° C in dark. Do not freeze.

Target Information

Target Name N-Cadherin
Alternative Names Cadherin 2; CDHN; Cadherin 2 Type 1 N-Cadherin (Neuronal); Neural Cadherin; N-Cadherin 2; Cadherin-2; CDw325; CD325; NCAD; Calcium-Dependent Adhesion Protein Neuronal; CD325 Antigen; N-Cadherin 1; ARVD14; ACOGS; CDH2
Related Disease Agenesis Of Corpus Callosum Cardiac Ocular And Genital Syndrome; Arrhythmogenic Right Ventricular Dysplasia Familial 14
Gene ID 1000
UniProt ID P19022
Target Overview Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.
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!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

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