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This product is an unconjugated anti-Human Dermcidin Monoclonal antibody (G-81) generated from the Mouse. This antibody can be used for WB, IP, IF, IHC.
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specifications |
|
|---|---|
| Antibody Isotype | IgM, κ |
| Clone | G-81 |
| Applications | WB; IP; IF; IHC |
| Target | Dermcidin |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | human dermcidin chromatographically purified from human sweat |
| Format | Liquid |
| Buffer | PBS |
| Storage | Store at 4° C. |
Target Information |
|
|---|---|
| Target Name | Dermcidin |
| Alternative Names | Preproteolysin; AIDD; DSEP; Diffusible Survival/Evasion Peptide; Proteolysis Inducing Factor; Survival Promoting Peptide; DCD-1; HCAP; PIF; DCD |
| Related Disease | Root Caries; Netherton Syndrome |
| Gene ID | 117159 |
| UniProt ID | P81605 |
| Target Overview | DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues. As a survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG. |
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Datasheet