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Mouse Anti-Human CD95 IgM Monoclonal Antibody (EOS9.1) (CAT#: NGM-318)

This product is an unconjugated anti-Human CD95 Monoclonal antibody (EOS9.1) generated from the Mouse. This antibody can be used for FC, Func.

Please feel free to contact us for a quote and further discussion with our scientists. Datasheets

specifications

Antibody Isotype IgM, κ
Clone EOS9.1
Applications FC; Func
Target CD95
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Human
Immunogen P815 cells transfected with human CD95
Format Liquid
Buffer PBS
Storage Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles.

Target Information

Target Name CD95
Alternative Names Fas Cell Surface Death Receptor; Tumor Necrosis Factor Receptor Superfamily, Member 6; Fas (TNF Receptor Superfamily, Member 6); Apoptosis-Mediating Surface Antigen FAS; TNF Receptor Superfamily Member 6; FASLG Receptor; CD95 Antigen; TNFRSF6; APO-1; APT1; FAS1; Mutant Tumor Necrosis Receptor Superfamily Member 6; Apoptosis Signaling Receptor FAS; APO-1 Cell Surface Antigen; Apoptosis Antigen 1; Apo-1 Antigen; Fas AMA; ALPS1A; FASTM; FAS
Related Disease Autoimmune Lymphoproliferative Syndrome; Lymphoproliferative Syndrome
Gene ID 355
UniProt ID P25445
Target Overview Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
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KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.

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For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

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