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This product is an unconjugated anti-Human Caspase-2 Monoclonal antibody (18E809.3) generated from the Mouse. This antibody can be used for WB.
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specifications |
|
|---|---|
| Antibody Isotype | IgM, κ |
| Clone | 18E809.3 |
| Applications | WB |
| Target | Caspase-2 |
| Host | Mouse |
| Clonality | Monoclonal |
| Antibody Type | Primary antibody |
| Species Reactivity | Human |
| Immunogen | Recombinant human Caspase-2, aa., 400-450 |
| Format | Liquid |
| Buffer | Ascites with PBS and 0.2% Gelatin |
| Storage | Store at 4° C for short term and at -20° C or lower for long term. Avoid freeze-thaw cycles. |
Target Information |
|
|---|---|
| Target Name | Caspase-2 |
| Alternative Names | ICH1; Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 2; Protein Phosphatase 1 Regulatory Subunit 57; Protease ICH-1; Caspase-2; PPP1R57; CASP-2; NEDD-2; NEDD2; Neural Precursor Cell Expressed, Developmentally Down-Regulated 2; Caspase 2 Apoptosis-Related Cysteine Peptidase; CASP2 |
| Related Disease | Bladder Transitional Cell Papilloma; Retinal Ischemia |
| Gene ID | 835 |
| UniProt ID | P42575 |
| Target Overview | Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress. |
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Datasheet