CLOSE
SEARCH FOR
Book a Meeting
Mouse Anti-Chicken CD45 IgM Monoclonal Antibody (LT40) [PE] (CAT#: NGM-413)

This product is a conjugated anti-Chicken CD45 Monoclonal antibody (LT40) generated from the Mouse. This antibody can be used for FC.

Please feel free to contact us for a quote and further discussion with our scientists. Datasheets

specifications

Antibody Isotype IgM
Clone LT40
Applications FC
Target CD45
Host Mouse
Clonality Monoclonal
Antibody Type Primary antibody
Species Reactivity Chicken
Immunogen Chicken bursal lymphocytes
Format Liquid
Buffer PBS with sucrose
Storage Store at 4° C in dark. Do not freeze.

Target Information

Target Name CD45
Alternative Names Protein Tyrosine Phosphatase Receptor Type C; T200; Receptor-Type Tyrosine-Protein Phosphatase C; CD45 Antigen; GP180; L-CA; LCA; Protein Tyrosine Phosphatase, Receptor Type, C Polypeptide; T200 Leukocyte Common Antigen; Leukocyte Common Antigen; T200 Glycoprotein; CD45R; PTPRC; B220; LY5
Related Disease Severe Combined Immunodeficiency Autosomal Recessive T Cell-Negative B Cell-Positive Nk Cell-Positive; Hepatitis C Virus
Gene ID 386580
UniProt ID A0A1D5PR76
Target Overview Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. I acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.
  • Customer Reviews
  • Downloadable Resources

Click the button below to contact us or submit your feedback about this product.

KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.

Online Inquiry
For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.

CONTACT US

USA

Tel:

Fax:

Email:

Stay Up To Date
Subscribe

© 2024 Creative Biolabs All Rights Reserved