Click the button below to contact us or submit your feedback about this product.
This product is an unconjugated anti-CD3 Monoclonal Antibody (NGE05-TT) gernerated from the mouse.
Please feel free to contact us for a quote and further discussion with our scientists. Datasheets
specifications |
|
---|---|
Antibody Isotype | IgE |
Clone | NGE05-TT |
Target | CD3 |
Host | Mouse |
Clonality | Monoclonal |
Antibody Type | Primary antibody |
Species Reactivity | Human |
Immunogen | Human T lymphocytes |
Format | Liquid |
Buffer | Cell culture supernatant |
Storage | Store at -20°C. Avoid repeated freeze-thaw cycles. |
Target Information |
|
---|---|
Target Name | CD3 |
Alternative Names | CD3 T-Cell Co-Receptor; T-cell surface glycoprotein CD3 |
Related Disease | Type 1 diabetes; Autoimmune diseases; Cancers |
Target Overview | The CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8+ naive T cells) and also T helper cells (CD4+ naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. The TCR, ζ-chain, and CD3 molecules together constitute the TCR complex. |
Click the button below to contact us or submit your feedback about this product.
KINDLY NOTE
!! For Research Use Only. Our products and services are NOT intended for diagnostic or therapeutic applications.
!! Custom antibodies beyond the list can be tailored flexibly. Please directly Email us your specific demands.
© 2024 Creative Biolabs All Rights Reserved